|Wheeling Daily Intelligencer, Sept. 15, 1852|
As I mentioned, the story doesn't specifically say where this took place, but I think the real clue is in the owner of the second horse. The 1850 Census shows three Hoopes men living in Mill Creek Hundred -- Thomas, Jonathan, and William. Thomas and Jonathan both resided near Loveville, in the area around Lancaster Pike and Old Wilmington Road just below Brackenville Road. While both of them owned their own farms and William didn't, I think it was almost certainly William's horse that succumbed to the angry bees.
The reason for this is the identity of the second horse's owner -- Dr. McCabe. Dr. Robert McCabe lived along the south side of Little Baltimore Road, just east of the Mitchell farm now known as the Woodside Creamery. Not too far south of them, along North Star Road, lived Abner Woodward. In the household of Abner Woodward was a carpenter named William Hoopes. Hoopes was Woodward's brother-in-law, as Abner and William's sister Julia Ann Hoopes were married in 1839[thanks to Delaware21 for the info]. While it's not out of the realm of possibility that Dr. McCabe could have been making a house call a few miles east at Loveville, I think it's much more likely that the unfortunate horse belonged to William Hoopes.
And by the way, if you like horses and think this story was bad, don't even bother to read next week's.